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1.
Hypnotic prescription trends and patterns for the treatment of insomnia in Japan: analysis of a nationwide Japanese claims database.
BMC Psychiatry
; 23(1): 278, 2023 04 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-37081408
2.
Amine-free melanin-concentrating hormone receptor 1 antagonists: Novel 1-(1H-benzimidazol-6-yl)pyridin-2(1H)-one derivatives and design to avoid CYP3A4 time-dependent inhibition.
Bioorg Med Chem
; 24(11): 2486-503, 2016 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27112449
3.
Amine-free melanin-concentrating hormone receptor 1 antagonists: Novel non-basic 1-(2H-indazole-5-yl)pyridin-2(1H)-one derivatives and mitigation of mutagenicity in Ames test.
Bioorg Med Chem
; 24(11): 2504-18, 2016 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27117261
4.
Factors Associated with Prescriptions for an Orexin Receptor Antagonist Among Japanese Patients with Insomnia: Analysis of a Nationwide Japanese Claims Database.
Drugs Real World Outcomes
; 10(2): 271-281, 2023 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-36867350
5.
Demographic and clinical characteristics of patients with delirium: analysis of a nationwide Japanese medical database.
BMJ Open
; 12(9): e060630, 2022 09 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-36104137
6.
Incremental medical cost of delirium in elderly patients with cognitive impairment: analysis of a nationwide administrative database in Japan.
BMJ Open
; 12(12): e062141, 2022 12 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36521906
7.
Identification of MK-1925: a selective, orally active and brain-penetrable opioid receptor-like 1 (ORL1) antagonist.
Bioorg Med Chem Lett
; 19(16): 4729-32, 2009 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19564110
8.
Association between sleep disturbance in Alzheimer's disease patients and burden on and health status of their caregivers.
J Neurol
; 266(6): 1490-1500, 2019 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-30968171
9.
Corticotropin-releasing factor modulates maternal separation-induced ultrasonic vocalization in rat pups via activation of CRF1 receptor.
Brain Res
; 1234: 59-65, 2008 Oct 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-18703034
10.
Antipsychotic property of a muscarinic receptor agonist in animal models for schizophrenia.
Pharmacol Biochem Behav
; 91(1): 140-9, 2008 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-18651995
11.
Characteristics of object location memory in mice: Behavioral and pharmacological studies.
Physiol Behav
; 90(1): 116-24, 2007 Jan 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-17049363
12.
Podocan Is Expressed in Blood and Adipose Tissue and Correlates Negatively With the Induction of Diabetic Nephropathy.
J Endocr Soc
; 1(7): 772-786, 2017 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29264529
13.
A novel and selective melanin-concentrating hormone receptor 1 antagonist ameliorates obesity and hepatic steatosis in diet-induced obese rodent models.
Eur J Pharmacol
; 796: 45-53, 2017 Feb 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-27986627
14.
Development of a Novel Carbon-11 Labeled PET Radioligand for Melanin- Concentrating Hormone Receptor 1.
Curr Radiopharm
; 10(1): 35-40, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28034352
15.
A Selective Bombesin Receptor Subtype 3 Agonist Promotes Weight Loss in Male Diet-Induced-Obese Rats With Circadian Rhythm Change.
Endocrinology
; 158(5): 1298-1313, 2017 05 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28324017
16.
Identification of a novel spiropiperidine opioid receptor-like 1 antagonist class by a focused library approach featuring 3D-pharmacophore similarity.
J Med Chem
; 49(3): 847-9, 2006 Feb 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-16451050
17.
Ameliorative effect of N-desmethylclozapine in animal models of social deficits and cognitive functions.
Brain Res Bull
; 86(3-4): 146-51, 2011 Oct 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-21855612
18.
Effects of a novel metabotropic glutamate receptor 7 negative allosteric modulator, 6-(4-methoxyphenyl)-5-methyl-3-pyridin-4-ylisoxazonolo[4,5-c]pyridin-4(5H)-one (MMPIP), on the central nervous system in rodents.
Eur J Pharmacol
; 639(1-3): 106-14, 2010 Aug 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-20371227
19.
Identification of an orally active opioid receptor-like 1 (ORL1) receptor antagonist 4-{3-[(2R)-2,3-dihydroxypropyl]-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl}-1-[(1S,3S,4R)-spiro[bicyclo[2.2.1]heptane-2,1'-cyclopropan]-3-ylmethyl]piperidine as clinical candidate.
J Med Chem
; 52(14): 4091-4, 2009 Jul 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-19537798
20.
A novel class of cycloalkano[b]pyridines as potent and orally active opioid receptor-like 1 antagonists with minimal binding affinity to the hERG K+ channel.
J Med Chem
; 51(13): 4021-9, 2008 Jul 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-18537234